Table 3 Overview of 10 large studies on EGFR mutations in non‐small‐cell lung cancer (NSCLC).
Ethnicity | Subjects (n) | Mutation rate (%) | Deletions in exon 19 (%) | L858R (%) | Mutation rate (%) | |||
---|---|---|---|---|---|---|---|---|
Non‐smokers vs smokers | Female vs male | Adenocarcinoma vs other NSCLC | ||||||
Marchetti46 | White | 860 | 5 | 46 | 46 | 20 vs 2 | 19 vs 2 | 10 vs 0 |
Eberhard47 | White | 228 | 13 | 62 | 24 | 25 vs 12 | 13 vs 13 | 15 vs 11 |
Cappuzzuo67 | White | 89 | 17 | 53 | 47 | 46 vs 12 | 26 vs 12 | 20 vs 10 |
Shigematsu43 | White | 158 | 8 | 46 | 39 | 29 vs 3 | 20 vs 1 | 16 vs 1 |
East Asian | 361 | 30 | 56 vs 14 | 55 vs 19 | 48 vs 3 | |||
Kosaka55 | Japanese | 277 | 40 | 47 | 44 | 66 vs 22 | 59 vs 26 | 49 vs 2 |
Sonobe48 | Japanese | 154 | 39 | 57 | 37 | 79 vs 16 | 70 vs 19 | 55 vs 0 |
Tokumo72 | Japanese | 120 | 32 | 50 | 47 | 69 vs 15 | 57 vs 20 | 45 vs 3 |
Huang44 | Taiwanese | 101 | 39 | 33 | 51 | 47 vs 18 | 44 vs 32 | 55 vs 3 |
Sugio62 | Japanese | 469 | 29 | 45 | 55 | 54 vs 19 | 46 vs 21 | 42 vs 1 |
Yokoyama45 | Japanese | 349 | 29 | 40 | 39 | 54 vs 14 | 54 vs 15 | 42 vs 1 |