Table 1 Genotype and allele frequencies of the functional cartilage intermediate layer protein (CILP) +1184T→C single‐nucleotide polymorphism in the Finnish and Chinese samples.
Finnish | Chinese | Chinese (extreme set)* | ||||
---|---|---|---|---|---|---|
Genotype | Cases | Controls | Cases | Controls | Cases | Controls |
CC | 82 (0.36) | 73 (0.28) | 4 (0.01) | 4 (0.01) | 3 (0.01) | 4 (0.02) |
CT | 116 (0.50) | 141 (0.55) | 88 (0.26) | 83 (0.25) | 55 (0.26) | 51 (0.25) |
TT | 33 (0.14) | 43 (0.17) | 249 (0.73) | 251 (0.74) | 151 (0.72) | 150 (0.73) |
C | 280 (0.61) | 287 (0.56) | 96 (0.14) | 91 (0.13) | 61 (0.15) | 59 (0.14) |
T | 182 (0.39) | 227 (0.44) | 586 (0.86) | 585 (0.87) | 357 (0.85) | 351 (0.86) |
p Value (genotype) | 0.24 | 0.93 | 0.88 | |||
p Value (allele) | 0.14 | 0.71 | 0.93 |
*Sample set established by selecting the bottom 30% of the normalised distribution representing a control group of 70 males and 138 females with a mean (SD) age of 45 (4) years, and the top 30% representing a more severe patient group of 93 males, 119 females with lumbar disc disease with a mean (SD) age of 42 (9) years.