Figure 6 Proposed algorithm for the subtyping of patients with Fanconi anaemia (FA). A four‐step process is proposed for the subtyping of patients with Fanconi anaemia. Step 1 aims to confirm the diagnosis of Fanconi anaemia and somatic mosaicism. According to step 2, 85% of patients with Fanconi anaemia would be subtyped by retroviral complementation. The complementation groups of the remaining 15% of the patients could be discriminated by means of analyses shown in step 3. Finally, the subtype of rare complementation groups or the discovery of new complementation groups could be determined by means of different research approaches described in step 4. DEB, diepoxybutane; MMC, mitomycin C; PB, peripheral blood; Ub, ubiquitinated.