Table 2 Summary of gross pathology and organ weights.
Feature | Measure | Gross pathology and comments | |||
---|---|---|---|---|---|
Patient | Ref¶ | Patient | |||
SD600 | SD840 | SD600 | SD840 | ||
Age (years) | 13.7 | 23 | Small, well nourished | Small, well nourished | |
Corpse | |||||
Weight (kg) | 22.2* | 22† | |||
Length (cm) | 106.5‡ | 111§ | |||
Organ | |||||
Bone | NA | NA | Dysplastic | NA | |
Immune system | |||||
Thymus (g) | 2.1 | NA | 25 | Normal | NA |
Lymph node (g) | Normal | Normal | |||
Spleen (g) | 79.3 | 25 | 62 | Normal | Small, congested |
Native kidney (g, left/right) | 47/48 | 2 | 120 | Multiple cysts | Shrunken |
Transplant kidney (g) | 116 | 80 | Normal | Normal | |
Thyroid (g) | 4.9 | NA | 7 | ||
Bone marrow | Normal | Normal | |||
Vasculature | NA | NA | Diffuse fatty streaks in the aorta and pulmonary arteries | Diffuse fatty streaks in the aorta and pulmonary arteries | |
Brain (g) | 1100 | 1020 | 1300 | Normal | 1 small old cortical infarction, 2 fresh haemorrhagic cortical infarctions |
Lungs (g) | 305 | 420 | 1035 | Normal anatomy | Congested |
Heart (g) | 185 | 120 | 100 | Mild ventricular hypertrophy | Mild ventricular hypertrophy |
Genitalia | Normal Tanner stage 1 | Normal Tanner stage 5 | |||
Testes (g, left/right) | 0.94/1.01 | NA | 1.67 | Small | |
Pituitary | Normal anatomy | Normal anatomy |
NA, not available.
*50th centile for a 7.5‐year‐old boy.
†50th centile for a 6.5‐year‐old boy.
‡50th centile for a 4.25‐year‐old boy.
§50th centile for a 5.5‐year‐old boy.
¶Reference weights for a 6‐year‐old boy.