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| (NIH consensus development conference 1988)3 |
|---|
| • 6 or more café au lait macules (>0.5 cm in children or >1.5 cm in adults) |
| • 2 or more cutaneous/subcutaneous neurofibromas or one plexiform neurofibroma |
| • Axillary or groin freckling |
| • Optic pathway glioma |
| • 2 or more Lisch nodules (iris hamartomas seen on slit lamp examination) |
| • Bony dysplasia (sphenoid wing dysplasia, bowing of long bone ± pseudarthrosis) |
| • First degree relative with NF1 |
