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. 2008 May 10;2(2):164–181. doi: 10.1016/j.molonc.2008.05.001

Figure 2.

Figure 2

Induction of SnoN RNA levels by TGFβ is controlled by multiple signaling pathways. A, Immortalized normal ovarian epithelial cells and ovarian carcinoma cells were treated for 1 h with 50 pM TGFβ. RNA was extracted and qPCR analysis was performed to assess SnoN expression. The results are presented as RNA‐fold increases. B, Effect of LY294002 and JNK II inhibitor on SnoN RNA levels. OVCA429, HEY, T29, and T80 cells were treated with 50 μM PI3K inhibitor or 25 μM JNK II inhibitor for 12 h. RNA was extracted and qPCR analysis was performed to assess SnoN expression. The results are presented as RNA‐fold increases.