Using a tail cuff, weekly monitoring blood pressure showed that systolic blood pressure increased significantly after 6, 7, and 8 weeks in HS group, compared to NS group of SD rats, respectively (n = 6; P < 0.01). PowerLab measurement indicated that 4 weeks of a high salt diet (8%) did not significantly change MAP in SD rats in comparison with SD rats having a normal salt diet (n = 6; P >0.05); however, after 8 weeks of the dietary program, MAP was significantly higher in HS than NS group of SD rats (n = 6; P < 0.01).