Table 2 Characteristics of patients with serological failure among HIV‐positive and HIV‐negative patients.
HIV positive (n = 22/129) | HIV negative (n = 5/168) | p Value | |
---|---|---|---|
Failures by syphilis stage, n (%) | |||
Early | 4/32 (12.5) | 4/154 (2.6) | 0.01* |
Late or unknown duration | 18/97 (18.6) | 1/14 (7.1) | 0.3* |
Failure of fourfold drop, n (%) | 12/22 (55) | 3/5 (60) | NS* |
Early | 1/4 (25) | 2/4 (50) | NS* |
Late or unknown duration | 11/18 (61) | 1/1 (100) | NS* |
Median initial RPR titre | 1/8 | 1/8 | NS‡ |
Initial documented fourfold drop with subsequent fourfold increase (%) | 0 (0) | 0 (0) | NS* |
Fourfold increase without drop (%) | 10/22 (45) | 2/5 (40) | NS* |
Early | 3/4 (75) | 2/4 (50) | NS* |
Late or unknown | 7/18 (39) | 0/1 (0) | NS* |
Median initial RPR titre | 1/64 | 1/32 | NS† |
*χ2 test.
†K equality of medians test.
RPR, rapid plasma reagin; NS, not significant (p>0.05).