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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: J Mol Cell Cardiol. 2008 Sep 11;45(5):642–649. doi: 10.1016/j.yjmcc.2008.08.013

Figure 2. Delay of AP propagation between HL-1 cells and ESdC.

Figure 2

(A) For every excitation cycle of the HL-1 monolayer the delay between HL-1 and ESdC activity was determined during a period of independent activity (i.) and a period of transient synchronization (ii.). In i. the delay between HL-1 and ESdC activity is non-stationary (B). Separate analysis of the ESdCs and HL-1 spikes ISI revealed beating frequencies comparable to ESdCs and HL-1 cells in homocellular culture respectively (C). During transient synchronization (ii), the delay between the HL-1 cells and the ESdCs activity transiently stabilizes (D). At this point of time the ESdC’s ISI is an integral value of the HL-1’s ISI (E).