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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Anesthesiology. 2008 Aug;109(2):243–250. doi: 10.1097/ALN.0b013e31817f5c47

Figure 4.

Figure 4

Isoflurane induced significantly greater increase of cytosolic calcium than sevoflurane or desflurane only in wild type DT40 cells. Isoflurane (Iso) induced significantly more elevation of peak cytosolic calcium represented by the relative ratio (F340/F380) than sevoflurane (Sevo) or desflurane (Des) only in DT40 wild type (WT) cells (A and B). B. Data represents mean±SE from at least three separate experiments. ***means P<0.001 compared to IP3 receptor total knock-out (TKO) DT40 cells. ### means P<0.001 compared to DT40 WT cells treated with either Sevo or Des.