FIGURE 5.

Lateral pressure profiles of a DMPC bilayer consisting of 512 lipids at normal pressure (A) and at 1000 bar (B). The local lateral pressure, i.e., the difference between the lateral and normal components of the pressure tensor, is plotted as a function of the normal coordinate z of the bilayer (solid black line, z = 0 at the bilayer center). The error, calculated by averaging over time intervals and using error propagation for the smoothing procedure, is indicated by the gray shaded area. As a reference, the normalized, dimensionless number densities of various lipid components across the bilayer are given (dashed, black: phosphorus group; dotted, black: choline group; solid, gray: glycerol group; dot-dashed, black: sixth and seventh carbon atoms of the lipids; dashed, gray: water). C shows the difference between the pressure profiles at 1000 bar (bilayer at 1000 bar scaled to the thickness of the bilayer at normal pressure) and at 1 bar.