FIGURE 8.
Distance between the Cα atoms of residues involved in the proposed opening mechanism. The black line shows the analysis of MD2, and the red line shows the results for Y362F/R367S. (I) Intramonomeric distance between Tyr/Phe-362 and Asp-153 for each monomer. (III) Intermonomeric distance between Arg/Thr-367 and Asp-153 for each pair of adjacent monomers. (III′) Intermonomeric distance between Arg/Thr-367 and Thr-152 for each pair of adjacent monomers.