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Ionic changes accompanying propagation of the wave of spreading depression in the neuron-astrocyte network of Fig. 1 B. Column 1 gives intracellular concentrations in each of seven successive neurons in the network of K+ (A), Na+ (D), Ca2+ (G), and Cl− (J). Column 2 (middle) gives the corresponding extracellular concentrations, and column 3 gives the corresponding intracellular concentrations in each of seven successive astrocytes in the network.
