Table 2. Effects of CypA SNPs C1604G and A1650G on disease progression in the Amsterdam cohort of MSM.
SNP | Endpoint | Number | Events | RH (95% C.I.) | p-value |
C1604G | AIDS (CDC1987) | 334 | 211 | 0.91 (0.63–1.31) | 0.61 |
AIDS (CDC1993) | 333 | 235 | 0.84 (0.59–1.20) | 0.34 | |
CD4<200 cells/µl | 333 | 199 | 0.84 (0.57–1.23) | 0.37 | |
RNA>104.5 copies/ml | 331 | 232 | 1.02 (0.71–1.45) | 0.92 | |
A1650G | AIDS (CDC 1987) | 334 | 211 | 0.97 (0.71–1.33) | 0.87 |
AIDS (CDC1993) | 333 | 235 | 1.07 (0.80–1.43) | 0.67 | |
CD4<200 cells/µl | 333 | 199 | 0.98 (0.70–1.36) | 0.89 | |
RNA>104.5 copies/ml | 331 | 232 | 0.88 (0.65–1.20) | 0.42 |
P-values were from Cox proportional hazard analysis.