TABLE 3.
Detection of Gene Conversion Tracts from Aligned Sequences of hGH/CSH Genes Using SNPs as Markers
Haplotype |
Gene Conversion tract length (bp) |
|||||
---|---|---|---|---|---|---|
Gene | Variant | Frequency | Sequencea | Min | Max | |
GH2 | common | 98% | −322 | G…C −318 | 5 | 72 |
acceptor | 0.7% | C…A | ||||
CSHL1 | Donor | 100% | C…A | |||
CSH1 | common | 96.6% | +1086 | C… …T… …T… …A… …T… …A +1228 | 142 | 302 |
acceptor | 1.35% | A… …C… …G… …C… …C… …G | ||||
CSH2 | Donor | 100% | A… …C… …G… …C… …C… …G | |||
GH1 | common | 89.2% | −435 | G…………A −422 | 14 | 33 |
acceptor | 1.35% | A…………G | ||||
All others | Donor | 100% | A…………G | |||
GH1 | common | 50% | −68 | A….A −63 | 6 | 95 |
acceptor | 7.43% | G….T | ||||
CSH2/CSH1 | Donor | 100%/99.3% | G….T | |||
GH1 | common | 81.8% | −63 | A..G −60 | 4 | 63 |
acceptor | 4.05% | C..C | ||||
CSHL1 | Donor | 100% | C..C | |||
GH1 | common | 83.1% | −370 | G……G −363 | 8 | 60 |
acceptor | 15.5% | T……T | ||||
GH2 | Donor | 100% | T……T | |||
GH1 | common | 97.3% | +410 | C.T +412 | 3 | 23 |
acceptor | 2.03% | A.A | ||||
GH2 | Donor | 100% | A.A | |||
CSHL1 | common | 99.3% | +944 | CC…A +949 | 6 | 79 |
acceptor | 0.68% | TG…G | ||||
CSH1/CSH2 | Donor | 100% | TG…G |
location of a gene conversion tract on genomic sequence relative to the position of ATG of the acceptor gene; A denotes +1.