TABLE 4.
Estimation of Population Crossing-over and Gene Conversion Parameters (× 104) Using SNPs with MAF ≥10 %
Gene conversion tract lengtha |
Recombination parameters ρbp, γbp b |
Estonians | Han | Mandenkalu |
---|---|---|---|---|
Maximum PAC likelihood estimates [Li and Stephens, 2003] | ||||
NA | ρbp | 4.43 | 2.58 | 32.2 |
Pattern Matching method estimates [Padhukasahasram et al., 2006] | ||||
L=0b | ρbp | 5.0 | 4.0 | 40 |
L=100 | ρbp | 1.5 | 2.0 | 12 |
γbp | 120 | 70 | 500 | |
L=500 | ρbp | 0.6 | 0.8 | 4.0 |
γbp | 40 | 40 | 220 | |
Composite likelihood (CL) estimates [Hudson, 2001] | ||||
L=0 | ρbp | 2.59 | 2.48 | 31.31 |
L=100 | ρbp | 1.19 | 1.4 | 10.61 |
γbp | 107 | 65.9 | 372 | |
L=500 | ρbp | 0.86 | 1.18 | 9.02 |
γbp | 27.6 | 21.4 | 117 |
L is the gene conversion tract length
The population crossing-over rate per base pair, ρbp= 4Nerbp; the population gene-conversion rate per base pair, γbp=4Necbp.