Table IV.

Characterization of LN CD4⁺ T cells from naïve, H647-, AP331-, and H696- immunized SJL mice

T cells	H647	AP331	H696	Naïve
CD25+CD4+	13.7 ± 2.3 *	12.9 ± 1.6 *	19.9 ± 2.2 *,*,*	4.6 ± 2.2
FoxP3+	71.7 ± 10.0	53.3 ± 11.3	93.5 ± 7.1 *,*,*	47.1 ± 6.7
TGF-β+	21.7 ± 3.0 *,*	14.0 ± 7.1 *	32.0 ± 4.3 *,*	9.8 ± 2.6
GITR+	33.1 ± 7.6 *,*	32.0 ± 6.0 *,*	25.0 ± 1.3 *	21.2 ± 3.0
CCR6+	19.0 ± 1.5 *,*	16.0 ± 2.1 *	15.5 ± 1.7 *	12.3 ± 2.1
CTLA-4+	24.6 ± 6.5 *	19.1 ± 4.5	51.9 ± 7.6 *,*,*	24.8 ± 3.1
RANKL+	12.2 ± 2.0	10.9 ± 3.6	20.2 ± 1.6 *,*,*	6.5 ± 5.5
CD25−CD4+
FoxP3+	17.7 ± 2.3 *	16.4 ± 2.7 *	24.2 ± 1.2 *,*,*	12.7 ± 1.5
TGF-β+	2.1 ± 0.4	1.65 ± 0.6	3.16 ± 0.8	1.1 ± 0.1
GITR+	6.8 ± 0.5	6.8 ± 0.2	8.22 ± 1.05	5.5 ± 0.9
CCR6+	9.73 ± 0.5	10.9 ± 0.7	10.4 ± 0.8	8.8 ± 0.5
CTLA-4+	2.3 ± 0.6	5.3 ± 1.1	5.2 ± 1.2	2.5 ± 0.7
RANKL+	1.7 ± 1.1	2.5 ± 1.2	15.3 ± 5.2 *,*,*	0.5 ± 1.5

^*,P < 0.001 for naïve vs. treated groups; H696- vs. AP331-treated groups; and H647- vs. AP331-treated groups.