. Author manuscript; available in PMC: 2009 Nov 1.

Published in final edited form as: Clin Immunol. 2008 Sep 6;129(2):372–380. doi: 10.1016/j.clim.2008.07.022

Table 1. X chromosome inactivation is skewed and mirrors the flavocytochrome b₅₅₈ expression levels the patient and her mother.

The HUMARA gene was used to determine X chromosome inactivation described in the Methods. Results are shown on the left. %X_A/B represents the overall methylation of chromosome A or B for the indicated cell type (results shown from one blood draw). The percent of total neutrophils that express (%Pos) or do not express (%Neg) flavocytochrome b₅₅₈ based on flow cytometric analysis are shown on the right (n≥3).

	Methylated DNA				Flavocytochrome b₅₅₈ Expression
	Whole Blood		Neutrophils		Flavocytochrome b₅₅₈ Expression

	% X_A	% X_B	% X_A	% X_B	% Neg	% Pos
Control	59.7	40.3	64.0	36.0	0.0	100.0
Mother	55.1	44.9	61.5	39.5	39.1	61.9
Patient	95.7	4.3	96.4	3.6	92.9	7.1

Table 1. X chromosome inactivation is skewed and mirrors the flavocytochrome b558 expression levels the patient and her mother.

Table 1. X chromosome inactivation is skewed and mirrors the flavocytochrome b₅₅₈ expression levels the patient and her mother.