Table 2.

Tests for association between allele frequencies of ABCB1 single nucleotide polymorphisms (SNPs) and methadone dose

No.	SNP	Alleles	‘Lower’ dose na		‘Higher’ dose n		Point-wise P-value
			Allele 1b	Allele 2b	Allele 1	Allele 2
1	rs1045642	C/T	52	36	55	51	0.38
2	rs6949448	A/G	34	54	50	58	0.31
3	rs2235067	G/A	4	84	9	99	0.39
4	rs2032583	C/T	4	84	11	97	0.18
5	rs2032582	G/T	56	32	52	48	0.14
6	rs1922242	A/T	49	39	48	60	0.15
7	rs1128503	C/T	54	34	59	49	0.38
8	rs2520464	A/G	35	51	52	56	0.31
9	rs3789243	C/T	41	47	55	53	0.57

^aNumber of alleles.

^b‘1’ represents the first allele and ‘2’ represents the second allele.