Table 5.
Test for association between ABCB1 9-locus genotype patterns and methadone dose
MLGPs (order nos 1–9) | ‘Lower dose’ | ‘Higher dose’ | OR (95% CI) | Point-wise P-value | ||
---|---|---|---|---|---|---|
n | % | n | % | |||
HHGTHHHHH | 17 | 38.6 | 14 | 25.9 | 1.80 (0.70, 4.65) | 0.1968 |
CGGTGACGT | 5 | 11.4 | 4 | 7.4 | 1.60 (0.34, 7.73) | 0.7272 |
TAGTTTTAC | 2 | 4.5 | 11 | 20.4 | 0.19 (0.03, 0.98) | 0.0336 |
Others | 20 | 45.5 | 25 | 46.3 | ||
Total | 44 | 100 | 54 | 100 |
χ2 = 6.80; df = 3; overall P = 0.0787. MLGP, multi-locus genotype pattern; OR, odds ratio; CI, confidence interval.