Table 3 Comparison of telbivudine and lamivudine in patients with chronic hepatitis B.
HBeAg negative | |||
---|---|---|---|
Telbivudine | Lamivudine | p Value | |
52 weeks | |||
PCR negative (%) | 88 | 71 | <0.01 |
HBeAg loss (%) | |||
HBeAg seroconversion (%) | |||
Resistance | 2 | 7 | <0.01 |
Primary treatment failure (%) | 0 | 3 | |
76 weeks | |||
PCR negative (%) | 84 | 67 | <0.05 |
HBeAg seroconversion (%) |
HBeAg, hepatitis B e antigen; PCR, polymerase chain reaction.