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. 2007 Jan;83(975):32–39. doi: 10.1136/pgmj.2006.044826

Table 3 Comparison of telbivudine and lamivudine in patients with chronic hepatitis B.

HBeAg negative
Telbivudine Lamivudine p Value
52 weeks
PCR negative (%) 88 71 <0.01
HBeAg loss (%)
HBeAg seroconversion (%)
Resistance 2 7 <0.01
Primary treatment failure (%) 0 3
76 weeks
PCR negative (%) 84 67 <0.05
HBeAg seroconversion (%)

HBeAg, hepatitis B e antigen; PCR, polymerase chain reaction.