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. 2007 Jul;83(981):445–450. doi: 10.1136/pgmj.2007.059253

Table 1 Pre‐requisites for a pandemic.

H5N1
• New influenza A sub‐type: haemagglutinin (H) unrelated to immediate (pre‐pandemic) predecessor
• Little or no pre‐existing population immunity
• Causes significant clinical illness
• Efficient person‐to‐person spread X