Figure 3 (A) Conventional “white light” view of the distal ascending colon in a patient with pan‐colitis of >20 years duration. There is focal nodularity and interruption of the vascular net pattern. (B) Indigo carmine 0.5% chromoscopy shows an irregular mucosal architecture with a central neoplastic crypt architecture. The lesion endoscopically is suggestive of a dysplasia‐associated lesion mass. Endoscopic resection in this case is contraindicated. Pan‐proctocolectomy is the treatment of choice due to the high risk of colitis associated colorectal cancer.