Table 2 Mainz confocal endomicroscopy criteria for the prediction of intraepithelial colorectal neoplasia.

	Confocal endomicroscopy criteria
	Normal	Regenerative	Neoplastic
Vascular architecture	Hexagonal network delineating peri‐luminal crypt stroma	Hexagonal network with no or mild increase in capillary density	Distorted/dilated vascular architecture with elevated leakage. Irregular architecture with little/poor orientation to adjunct tissue
Crypt architecture	Regular luminal crypt openings/distribution. Goblet cells visualised at normal density	Star‐shaped luminal crypt openings ± focal aggregates of regular shaped crypts ± goblet cell depletion	Ridge‐lined irregular epithelial layer. Crypt/goblet cell attenuation. Irregular cell architecture with mucin depletion.