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. 2007 Aug;83(982):525–528. doi: 10.1136/pgmj.2006.052431

Table 3 Management of delirium3,9,10,12,21,22,23.

Algorithm for assessment and management of delirium
Index of suspicion
Low threshold for cognitive assessment/using screening tools, particularly where multiple predisposing and/or precipitating factors are present
 
Identification and diagnosis
Using, for example, DSM IV criteria or a validated tool, eg, Confusion Assessment Method
 
Evaluate reversibility and treat reversible causes
Review all medication. Assess, examine and investigate for reversible causes to a level appropriate for the patient
 
Pharmacological and non‐pharmacological management
Make optimal use of non‐pharmacological strategies and make the environment safe and comfortable. Where pharmacological agents required aim to use one drug at the lowest possible dose
Non‐pharmacological Pharmacological
Appropriate lighting for the time of day Predominantly neuroleptic effects:
Clocks and calendars to improve orientation Haloperidol 0.5–1 mg initially titrated to effect (use first line*)
Hearing/visual aids to reduce sensory impairment Olanzapine 2.5–5 mg daily
Encourage mobility and engagement in activities with other people Risperidone 0.5 mg twice daily
Avoid physical restraint, eg, cot sides Quietiapine 25 mg twice daily
Continuity of care from nursing staff Predominantly sedative effects:
Presence of family members, familiar objects, pictures of home and family Lorazepam 0.5 mg‐1 mg 4 hourly
Reduced abnormal distractions, eg, noise Midazolam 2.5 mg subcutaneously
Encourage adequate fluid intake to prevent dehydration and constipation Levopromazine 12.5 mg–25 mg
*except alcohol/drug withdrawal or Lewy body dementia where benzodiazepines are preferable
 
Involve family and carers
Explain, discuss and support. Involve in non‐pharmacological management. Obtain background and additional history, eg, pre‐admission cognitive status, drug and alcohol use
 
Review and reassess frequently