. 2007 Oct;83(984):638–642. doi: 10.1136/pgmj.2007.060533

Table 3 Commonly prescribed drugs used in hormone therapy for male‐to‐female transsexuals and their method of action³⁰.

• Cyproterone acetate → androgen receptor blocker

• Spironolactone → interferes with testosterone production

• Finasteride → prevents conversion of testosterone into active metabolite, DHT

• LHRH analogues → continuously stimulate pituitary gland, causing surge of LH followed by surge of testosterone, which ultimately leads to continuous testosterone inhibition by negative feedback

• Oestrogen → induces female characteristics

DHT, dihydrotestosterone; LH, luteinising hormone; LHRH, luteinising hormone releasing hormone.

Table 3 Commonly prescribed drugs used in hormone therapy for male‐to‐female transsexuals and their method of action30.

Table 3 Commonly prescribed drugs used in hormone therapy for male‐to‐female transsexuals and their method of action³⁰.