Table 1. Clinical manifestations of severe Streptococcus pyogenes infection, United Kingdom, 2003–2004.
| Manifestation | All case-patients, no. (%)* | Children <16 y of age, no. (%) | Adults 16–60 y of age, no. (%) | Adults >60 y of age, no. (%) |
|---|---|---|---|---|
| Skin/soft tissue infection | 1,099 (42) | 85 (27) | 479 (39) | 531 (50) |
| Cellulitis | 881 (34) | 59 (19) | 362 (30) | 457 (43) |
| Necrotizing fasciitis | 136 (5) | 4 (1) | 87 (7) | 45 (4) |
| Abscess | 134 (5) | 6 (2) | 112 (9) | 16 (2) |
| Erysipelas | 24 (1) | 2 (1) | 9 (1) | 13 (1) |
| Bacteremia with no defined focus | 558 (21) | 77 (24) | 228 (19) | 252 (24) |
| Respiratory tract infection | 434 (17) | 66 (21) | 187 (15) | 181 (17) |
| Pneumonia | 309 (12) | 27 (8) | 139 (11) | 143 (13) |
| Other lower respiratory tract infection | 62 (2) | 6 (2) | 26 (2) | 30 (3) |
| Pharyngitis/tonsillitis | 51 (2) | 26 (8) | 16 (1) | 9 (1) |
| Ear infection | 22 (1) | 8 (3) | 9 (1) | 5 (<1) |
| Epiglottitis | 17 (1) | 2 (1) | 10 (1) | 5 (<1) |
| Sinusitis | 6 (<1) | 4 (1) | 0 | 2 (<1) |
| Septic arthritis | 220 (8) | 40 (13) | 114 (9) | 66 (6) |
| Puerperal sepsis | 58 (2) | 0 | 58 (5) | 0 |
| Acute abdominal infection† | 49 (2) | 5 (2) | 31 (3) | 12 (1) |
| Cardiac infection‡ | 48 (2) | 2 (1) | 36 (3) | 10 (1) |
| Meningitis | 37 (1) | 18 (6) | 12 (1) | 7 (1) |
| Total | 2,611 (100) | 318 (100) | 1,225 (100) | 1,064 (100) |
*Includes patients without age information. †Includes 14 patients with peritonitis, 1 with appendicitis, and 1 with pancreatitis. ‡Includes 42 patients with endocarditis, 4 with pericarditis, 1 with myocarditis, 1 with myocarditis and pericarditis.