Table 2. Molecular characteristics of the non–multidrug-resistant methicillin-resistant Staphylococcus aureus isolates, Geneva University Hospitals, 2002–2005*.
Isolates | No. strains | PVL | Exfoliatin toxin A | TSST-1 |
agr type |
Main MLST types | |||
---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | ||||||
SCCmec I | 21 | 0 | 0 | 11 | 9 | 11 | 1 | 0 | 5,149 |
SCCmec II | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | ND |
SCCmec III | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | ND |
SCCmec IV† | 109 | 53 | 11 | 9 | 20 | 24 | 65 | 0 | 1, 5, 8, 22, 30, 72, 80, 85, 88, 149 |
SCCmec V | 15 | 6 | 0 | 1 | 8‡ | 3 | 4 | 0 | 1, 30, 59, 85, 152 |
SCCmec NT | 4 | 1 | 0 | 1 | 1 | 1 | 2 | 0 | ND |
Total§ | 151 | 60 | 11 | 22 | 38 | 40 | 73 | 0 |
*PVL, Panton-Valentine leukocidin; TSST-1, toxic shock syndrome toxin 1; agr, accessory gene regulator; MLST, multilocus sequence typing; SCCmec, staphylococcal cassette chromosome mec; ND, not determined; NT, nontypeable. †Two isolates had recombinases identical to SCCmec IVe on the basis of sequence information; 4 isolates were not typeable. ‡One isolate was characterized after PCR amplification and sequencing as previously described (12). §A total of 92 strains had toxins, but the total number of toxin genes detected was 93 because 1 isolate contained PVL and TSST-1.