Table. Incidence of resistance/decreased susceptibility to key antimicrobial agents in isolates of Salmonella enterica serovars Typhi and Paratyphi A, United Kingdom, 2001–2006*.
| Year | No. studied | % S. Typhi resistant to |
No. studied | % S. Paratyphi A resistant to |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C | A | Tm | CpL | CpH | C | A | Tm | CpL | CpH | |||
| 2001 | 170 | 24 | 23 | 23 | 35 | 0 | 232 | 28 | 27 | 27 | 23 | 2 |
| 2002 | 150 | 18 | 17 | 17 | 35 | 1 | 149 | 10 | 9 | 10 | 39 | 3 |
| 2003 | 218 | 20 | 20 | 21 | 43 | 1 | 177 | 17 | 18 | 17 | 65 | 12 |
| 2004 | 215 | 23 | 23 | 24 | 47 | 2 | 221 | 5 | 5 | 5 | 70 | 14 |
| 2005 | 222 | 29 | 29 | 29 | 62 | 2 | 217 | 7 | 7 | 7 | 60 | 12 |
| 2006 | 240 | 23 | 24 | 24 | 68 | 2 | 278 | 2 | 3 | 2 | 64 | 9 |
*C, chloramphenicol; A, ampicillin, Tm, trimethoprim, CpL, ciprofloxacin MIC 0.25–1.0 mg/L; CpH, ciprofloxacin MIC >1.0 mg/L. No isolates exhibited resistance to ceftriaxone or cefotaxime; of 50 S. Typhi and 40 S. Paratyphi A isolated in 2005 and 2006, the MIC to azithromycin by E test (AB Biodisk, Solna, Sweden) was not greater than 8 mg/L for S. Typhi and 12 mg/L for S. Paratyphi A, which corresponds to those of drug-sensitive controls of the respective serotypes.