| Drugs to test |
First-line DST; isoniazid and rifampin most important because empiric treatment regimen and further DST may follow |
| Reproducibility |
Because drug-resistant samples identified by regional DST, then referred to National Reference Laboratory for DST to second-line drugs, sensitivity most important |
| Sample source |
Direct method optimal for processing
at local health clinic to minimize turnaround time |
| Cost per sample |
Low cost |
| Time to obtain result |
Rapid |
| Technical demand |
Less technically demanding, less processing time |
| Biologic safety risk |
Low biosecurity risk |
| Required equipment |
Limited additional equipment
(refridgerated centrifuge) procured and maintained in local site |
| Reagents and supplies |
Commonly used reagents and supplies available through local vendors is preferable |
