Table 5. Syndrome variation that can be explained by either the pathogen counts, 
seasonal terms, or pathogen counts and seasonal terms together*.

Syndrome data	Pathogens, %	Pathogens and seasonal terms, %	Seasonal terms, %
Absenteeism	68	80	79
GP	86	89	75
Pharmacy	80	87	77
Hospitalization	84	88	75
Laboratory submissions	61	63	53
Mortality	78	78	52

*Estimated by 3 different R² values for each registry: 1) for the syndromes explained by pathogen counts alone; 2) after adding seasonal terms to the pathogen model; and 3) for the syndromes explained by seasonal terms alone (sine and cosine parameters). GP, general practice.