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. 2008 Aug;14(8):1320–1322. doi: 10.3201/eid1408.080049

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Phylogenetic trees constructed on the basis of A) 240 nucleotides, RdRp region, from open reading frame (ORF) 1, and B) 311 nucleotides from ORF2. Each tree was generated by using the neighbor-joining method; the distance matrix was calculated by using the Kimura 2-parameter method. The robustness of the trees was determined by bootstrap for 1,000 replicates. Values >70% are shown at the nodes. The major branches represent hepatitis E virus genotypes. Scale bar indicates 0.05 substitutions per nucleotide position.