Table 2.
Mutant ID |
Gene position |
Nucleotide substitution |
Amino acid position |
Amino acid substitution |
Fitnessa | SEb |
---|---|---|---|---|---|---|
G19 | Not in P3 | Unknown | Unknown | Unknown | 5.53 | 0.11 |
g18 | 1603 | G → A | 535 | D → N | 6.23 | 0.07 |
g27 | 1016 | C → T | 339 | P → H | 6.41 | 0.14 |
g25 | 23 | A → G | 8 | E → G | 6.48 | 0.05 |
g24 | 22 | G → A | 8 | E → K | 6.60 | 0.10 |
g9 | 1661 | A → C | 554 | D → A | 6.73 | 0.11 |
g2 | 1661 | A → T | 554 | D → V | 6.78 | 0.07 |
g6 | 1661 | A → G | 554 | D → G | 6.83 | 0.05 |
g14 | 1663 | C → T | 555 | L → F | 6.86 | 0.05 |
g22 | 13 | G → A | 5 | G → S | 6.94 | 0.09 |
g36 | 1660 | G → A | 554 | D → N | 6.97 | 0.06 |
g15 | 1598 | A → C | 533 | D → A | 7.02 | 0.10 |
g8 | 434 | A → G | 145 | D → G | 7.03 | 0.10 |
g5 | 437 | A → G | 146 | N → S | 7.19 | 0.11 |
g20 | 1546 | A → G | 516 | T → A | 7.26 | 0.06 |
g29 | 534 | G → C | 178 | E → D | 7.56 | 0.10 |
Fitness was measured as the log10 of the number of phages per plaque per 24 h on plates
Based on six replicates