Table 3.
A summary of the statistical results for two viral data sets
Phage | Obs. | Shifta | H0: k = 0 (τ̂) | HA: k ≠ 0 (k̂, τ̂) | Likelihood ratio testb |
Approximate methodb |
||||
---|---|---|---|---|---|---|---|---|---|---|
−2logΛ | df | p | k̂ | df | 95% CI | |||||
ID11 | 9 | 1 | 0.68 | (−1.0, 1.02) | 9.42 | 8 | 0.006 | −1.06 | 7 | (−2.64, −0.57) |
2 | 0.63 | (−1.0, 0.89) | 9.04 | 7 | 0.006 | −1.08 | 6 | (−2.93, −0.55) | ||
3 | 0.50 | (−1.0, 0.69) | 8.01 | 6 | 0.009 | −1.00 | 5 | (−3.08, −0.49) | ||
ϕ6 | 16 | 1 | 1.33 | (−1.0, 2.03) | 17.30 | 15 | <0.001 | −1.00 | 14 | (−1.83, −0.63) |
2 | 0.68 | (−1.0, 1.33) | 8.98 | 14 | 0.021 | −0.65 | 13 | (−1.22, −0.40) |
This designates the threshold used for the analysis. 1 indicates the fitness of the lowest fitness mutant; 2, the second lowest; etc. Shifting further than shown results in a failure to reject at the 5% significance level
The likelihood ratio test and approximate method are described under Materials and Methods