Local effect of TMS stimulation on BOLD signal from left PMd Region of interest (ROI) analysis for TMShigh > TMSlow, irrespective of grip, in an a priori defined ROI (sphere of 15 mm diameter, illustrated by the white circle) centered around the site of stimulation in the left PMd (x,y,z: -24, -14, 62). TMShigh vs TMSlow induced more activity in this area (P < 0.05, corrected for multiple comparisons at the cluster level within ROI). Thus, TMS at 110% of resting motor threshold evoked a local activity increase, relative to stimulation at the low intensity (70% active motor threshold). Activations are projected onto the average normalized structural scans of all participants. R = right.