Table 3.
Expression of candidate maker proteins in vitretional diseases. The value x, as represented by “+”, denotes the fold-indicate of each protein compared to control. The candidate marker proteins that are ranked higher then 10th in Fig. 6 are indicated by “+”. The asterisk (*) indicates the ranking of some notable proteins in their signal to noise (S2N) values.
| NPDR | PDR | RRD | PVR | |
|---|---|---|---|---|
| AAT | + | + | + | ++ |
| APOA4 | + | + | + | ++ |
| ALB | + | + | *33rd (+++) | ++ |
| TF | + | *11th (+) | *35th (++) | ++ |
| A1BG | + | + | ||
| C3 | +++++(52-fold); + | + | ||
| FGG | ++ | +++++(173-fold); + | ||
| GC | + | + | ||
| APOA1 | ++ | |||
| AZGP1 | + | + | ||
| PEDF | ++; +; +++; ++ | + | ||
| CLU | ++++ | *22nd; *24th; *28th (al ++) | ||
| CTSD | +++; +++; +++ | |||
| TTR | *23rd; *28th (both++) | + | ||
| RBP4 | ++ | |||
| SERPINC1 | ++ |
Fold-increase compared to control:
+; 3≤x<10
++; 10≤x<20
+++; 20≤x<30
++++; 30≤x<40
+++++; larger then 40-fold (shown in parenthesis)
FGB was detecated in all NPDR samples (12/12) in contrast to fibrin beta (5/12).
FGB was detecated in 11/16 PDR samples (12/12) in contrast to fibrin beta (6/16).