Table 3.1. Effect of local conformational coupling on the lowest-frequency normal twisting mode of a 100 bp generic DNA homopolymer*.
Coupled variables | † (cm-1) | † (cm-1) | ΔC§ (%) |
---|---|---|---|
0.186 | 0.186 | ||
Tilt-Roll | 0.186 | 0.186 | 0.0 |
Tilt-Twist | 0.185 | 0.185 | -0.5 |
Tilt-Shift | 0.186 | 0.186 | 0.0 |
Tilt-Slide | 0.186 | 0.186 | 0.0 |
Tilt-Rise | 0.186 | 0.186 | 0.0 |
Roll-Twist | 0.192 | 0.193 | 8.6 |
Roll-Shift | 0.186 | 0.186 | 0.0 |
Roll-Slide | 0.186 | 0.186 | 0.0 |
Roll-Rise | 0.186 | 0.186 | 0.1 |
Twist-Shift | 0.185 | 0.185 | -0.6 |
Twist-Slide | 0.185 | 0.186 | 0.0 |
Twist-Rise | 0.182 | 0.193 | 8.2 |
Shift-Slide | 0.186 | 0.186 | 0.0 |
Shift-Rise | 0.186 | 0.186 | 0.0 |
Slide-Rise | 0.186 | 0.186 | 0.0 |
Roll-Twist,Twist-Rise | 0.188 | 0.210 | 28.3 |
Twist-Slide,Twist-Rise | 0.181 | 0.199 | 14.7 |
Roll-Twist,Twist-Slide | 0.194 | 0.198 | 13.6 |
Roll-Twist,Twist-Slide,Twist-Rise | 0.184 | 0.214 | 33.1 |
Dimeric rest state: .
Frequencies of DNA chains subject to the following global constraints: , unrestrained chain ends; , ends restrained to equilibrium length.
Change in torsional modulus of the restrained duplex subject to given conformational coupling compared to that (C = 1.98 × 10-19 erg-cm) of the unrestrained, generic molecule with independent fluctuations of base-pair step parameters.