Table 3.
General linear model testing the relationship between baseline uric acid tertiles and follow-up handgrip after adjusting for baseline handgrip and other relevant confounders. The initial fully adjusted model was reduced to a "most parsimonious" model by using backward selection (p < 0.05).
| Final Model: Obs = 497; F = 432; Prob > F < 0.001; Adjusted R2 = 0.782. | ||
|---|---|---|
| Follow-up Handgrip (Kg) | β ± SE (β) | p | 
| Age (years) | −0.35 ± 0.04 | < 0.001 | 
| Female sex | − 8.70 ± 0.61 | < 0.001 | 
| Uric Acid tertiles (trend) | 0.70 ± 0.29 | 0.016 | 
| - Uric Acid 1st tertile (< 4.4 mg/dL) (reference) | ------ | ------ | 
| - Uric Acid 2nd tertile (4.4 – 5.5 mg/dL) | 1.08 ± 0.53 | 0.047 | 
| - Uric Acid 3rd tertile (> 5.5 mg/dL) | 1.41 ± 0.58 | 0.015 | 
| Baseline Handgrip (Kg) | 0.41 ± 0.03 | < 0.001 | 
The initial fully adjusted model included: age, sex, BMI, hypertension, chronic heart failure, HDL-cholesterol, triglycerides, creatinin, HOMA-R index, α- and γ-tocopherol, C-reactive protein, interleukin 1 receptor antagonist, interleukin 6, vitamin C intake, number of medications, use of diuretics and baseline handgrip.