. Author manuscript; available in PMC: 2009 Sep 1.

Published in final edited form as: Mech Ageing Dev. 2008 Apr 30;129(9):522–527. doi: 10.1016/j.mad.2008.04.008

Table 4.

General linear model testing the relationship between baseline uric acid tertiles and follow-up knee extension torque after adjusting for baseline knee extension torque and other relevant confounders. The initial fully adjusted model was reduced to a "most parsimonious" model by using backward selection (p < 0.05).

Final Model: Obs = 497; F = 145; Prob > F < 0.001; Adjusted R² = 0.657.
Follow-up Knee Extension Torque (Newton dm)	β ± SE (β)	p
Age (years)	− 2.97 ± 0.71	< 0.001
Female sex	− 82.40 ± 9.72	< 0.001
Uric Acid Tertile (trend)	9.86 ± 4.62	0.040
- Uric Acid 1^st tertile (< 4.4 mg/dL) (reference)	------	------
- Uric Acid 2^nd tertile (4.4 – 5.5 mg/dL)	18.35 ± 9.01	0.048
- Uric Acid 3^rd tertile (> 5.5 mg/dL)	20.48 ± 9.75	0.041
Body Mass Index (kg/m²)	2.66 ± 1.00	0.008
n° of medications	− 5.99 ± 1.96	0.002
Baseline Knee Extension Torque (Newton dm)	0.39 ± 0.03	< 0.001

The initial fully adjusted model included: age, sex, BMI, hypertension, chronic heart failure, HDL-cholesterol, triglycerides, creatinin, HOMA-R index, α- and γ-tocopherol, C-reactive protein, interleukin 1 receptor antagonist, interleukin 6, vitamin C intake, number of medications, use of diuretics and baseline knee extension torque.