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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Exp Neurol. 2008 Jun 24;213(1):229–237. doi: 10.1016/j.expneurol.2008.06.010

Fig.4. In vivo effect of chronic administration of NDGA on glutamate uptake.

Fig.4

(A) Glutamate uptake was measured at 37 °C in synaptosomes prepared from spinal cord of non-transgenic mice. (B) Glutamate uptake was measured in spinal cord synaptosomes prepared from non-transgenic mice treated with placebo or NDGA containing pellets. Delivery of 30 mg of NDGA over 30 days was achieved by implanting 3 pellets, tailored to deliver 10mg over 10 days, at 10 day intervals (from day 0 – 20). Uptake was measured 10 and 30 days after the implantation of the first pellet.