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Potential Non-growth Uses of rhIGF-I and Their Level of Development
| Potential indication | Preclinical data |
Non- randomized trials |
Randomized controlled trials |
|---|---|---|---|
| Enhancing insulin signaling | |||
| Type 1 Diabetes mellitus | ✓ | ✓ | |
| Type 2 Diabetes mellitus | ✓ | ✓ | |
| Type A Insulin Resistance | ✓ | ✓ | |
| Rabson Mendenhall Syndrome | ✓ | ✓ | |
| Lipodystrophy | ✓ | ✓ | |
| Diseases of the Central Nervous System | |||
| Dementia | ✓ | ||
| Hearing loss | ✓ | ||
| Spinal cord injury | ✓ | ||
| Cardiovascular disease | ✓ | ||
| Osteoporosis | ✓ | ✓ | |
