Table 6. Levels of glycated proteins in the left and right lens of rats 13 weeks after injection.
| Group I (n=5) | Group II (n=7) | Group III (n=5) | Group IV (n=7) | Group V (n=7) | Group VI (n=5) | Group VII (n=10) | ||
|---|---|---|---|---|---|---|---|---|
| Glycated proteins | L |
4.2±0.4 |
4.0±1.2** |
3.4±0.3** |
3.7±0.5** |
4.5±0.7** |
4.1±0.3** |
5.4±0.5* |
| R | 4.2±0.4 | 4.1±0.5** | 3.6±0.6** | 3.5±0.3** | 4.9±0.8** | 4.3±0.5** | 5.4±0.5* | |
The data are the mean±SD. Glycated lens protein is expressed as mmoles HMF/mole protein. An asterisk indicates that p<0.001 when group I is compared with group VII, and a double asterisk indicates that p<0.001 for groups II-VI when compared with group VII. There were no significant differences between the left and right lens in any of the five treated diabetic groups. L: the left eyes that served as the treated eyes; R: the right eyes that served as the control eyes. The number of lens (n) represents equally in both the left and right eyes in each group. Group I: Normal; Group II: Carnosine treated (5 mg/ml); Group III: Carnosine treated (10 mg/ml); Group IV: Aspirin treated; Group V: Aminoguanidine treated (1 mg/ml); Group VI: Aminoguanidine treated (2 mg/ml); and Group VII: Untreated diabetic.