Fig. 1.
Three-dimensional representation of the overall structure of the GC-1008–TGF-β3 complex shown as ribbon diagram. View is down the 2-fold symmetry axis according to Groppe et al. (14). The identical monomers of the TGF-β3 homodimer are depicted in blue and red. The bound Fab fragments are shown in yellow (heavy chain) and green (light chain).