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. Author manuscript; available in PMC: 2009 Dec 3.
Published in final edited form as: Eur J Pharmacol. 2008 Oct 9;599(1-3):36–43. doi: 10.1016/j.ejphar.2008.09.043

Fig. 4.

Fig. 4

Inhibition of [3H]cAMP accumulation by morphine (A) or DAMGO (B) in CHO cells stably expressing rpMOR or hMOR. A range of opioid agonist concentrations were used in order to determine the concentration for 50% inhibition (IC50) and maximal inhibition (Imax). Individual values are reported in Table 2. [3H]-cAMP accumulation is plotted as percent versus that in cells treated with 10 μM forskolin only. For each condition, 3−5 independent experiments were performed in triplicate (error bars indicate S.E.M.).