Table 3.
Hemodynamic parameters during baseline and head up tilt
| Controls | Diabetes | Hypertension | Stroke | Groups&side | |
|---|---|---|---|---|---|
| BASELINE | |||||
| BFV MCAR (cm/s) | 54.4±15.1 | 46.3±16.5 | 60±15.4 | 52.2±17 | 0.19 |
| BFV MCAL (cm/s) | 55.6±13.7 | 49.9±15.7 | 55.9±16.5 | 51.2±22 | |
| Heart rate (bpm) | 64.8±8.3*** | 69.8±17.4 | 70.5±9.6 | 73.1±12.4 | 0.0008 |
| SBP (mm Hg) | 121±14*** | 130±19 | 148±14 | 135±14 | <0.0001 |
| DBP (mm Hg) | 65.96+10.1*** | 64.9+10* | 82.4+16.9 | 73.7+14.2 | <0.0001 |
| CVR MCAR (mm Hg/cm/s) | 1.7±0.6** | 2.2±0.9 | 1.9±0.6 | 2.1±0.9 | 0.0034 |
| CVR MCAL (mm Hg/cm/s) | 1.6±0.4*** | 1.9±0.6 | 2.0±0.7 | 2.2±0.9 | |
| PI MCAR (cm/s) | 0.7±0.1* | 0.7±0.2 | 0.8±0.2 | 0.8±0.2 | 0.0005 |
| PI MCAL (cm/s) | 0.7±0.1** | 0.7±0.1 | 0.8±0.2 | 0.9±0.3 | |
| Baseline EtCO2 (mm Hg) | 37.3±7.7 | 34.9±5.6 | 36.6±6.5 | 35.9±3.8 | 0.33 |
| TILT | |||||
| BFV MCAR (cm/s) | 48.4±14.0 | 44.7±14.0 | 55.6±18.1 | 50.1±17.9 | 0.41 |
| BFV MCAL (cm/s) | 49.5±12.0 | 46.9±12.8 | 52.5±16.9 | 49.3±21.6 | |
| HR (bpm) | 77.4±10.8 | 80.0±12.7 | 75.2±12.2 | 80.9±12.9 | 0.02 |
| SBP (mm Hg) | 122±17.0*** | 131±15.3 | 156±14.0 | 142±16.7 | <0.0001 |
| DBP (mm Hg) | 73.2±11.0*** | 73.5±12.1 | 89.2±19.4 | 83.4±18.7 | <0.0001 |
| CVR MCAR (mm Hg/cm/s) | 1.6±0.0.6** | 1.9±0.8 | 1.8±0.0.7 | 1.9±0.9 | 0.0096 |
| CVR MCAL (mm Hg/cm/s) | 1.5±0.4*** | 1.7±0.0.7 | 1.9±0.0.7 | 1.8±0.0.7 | |
| PI MCAR (cm/s) | 0.7±0.2 | 0.7±0.3 | 0.8±0.2 | 0.9±0.6 | 0.01 |
| PI MCAL (cm/s) | 0.7±0.2 | 0.8±0.2 | 0.8±0.2 | 0.8±0.2 | |
| Baseline EtCO2 | 32.1±4.3 | 32.4±4.3 | 34.0±4.5 | 33.3±3.3 | 0.1 |
Values are expressed as percentages or mean ± SD, model was adjusted for age and sex, MANOVA used for paired variables
•indicates values that were significantly different in control group compared to other groups
*
p<0.05
**
p<0.01
***
p<0.0001
•CVR tilt was adjusted for position