Table 5.
Multivariate-Adjusted Proportions of Unilateral Breast Cancer Survivors With SF-36 Scores 1 SD Below the Mean SF-36 Scores for the IWHS Cohort
| SF-36 Summary and Subscales | IWHS Cohort (n = 20,844)
|
% of Women
|
P‡ | P§ | |||
|---|---|---|---|---|---|---|---|
| Mean Score | SE | Women Without Lymphedema or Arm Symptoms (n = 708)% | Women With Diagnosed Lymphedema (n = 104)*% | Women With Arm Symptoms Without Lymphedema (n = 475)†% | |||
| Physical component summary | 41.4 | 0.07 | 25.3 | 40.4 | 34.4 | .005 | .003 |
| Mental component summary | 53.0 | 0.07 | 21.5 | 27.9 | 31.8 | .48 | .0002 |
| Vitality/fatigue | 49.0 | 0.06 | 16.5 | 25.0 | 22.3 | .12 | .04 |
| Physical functioning | 40.1 | 0.07 | 18.6 | 29.8 | 26.1 | .03 | .007 |
| Role limitations, physical | 41.8 | 0.08 | 18.8 | 28.8 | 27.6 | .06 | .001 |
| Mental health | 51.8 | 0.06 | 14.8 | 15.4 | 23.8 | 1.00 | .0003 |
| Role limitations, emotional | 47.1 | 0.08 | 19.2 | 27.9 | 31.4 | .16 | < .0001 |
| Social functioning | 49.0 | 0.07 | 15.4 | 22.1 | 25.9 | .32 | < .0001 |
| Bodily pain | 46.4 | 0.07 | 21.2 | 29.8 | 31.8 | .18 | .0001 |
| General health | 47.5 | 0.06 | 17.0 | 27.9 | 28.6 | .03 | < .0001 |
Abbreviations: SF-36, Medical Outcomes Study Short Form-36; SD, standard deviation; IWHS, Iowa Women's Health Study.
Women with lymphedema include participants who self-reported having had a diagnosis of lymphedema on the 2004 survey.
Women with arm symptoms without diagnosed lymphedema include participants who denied having a known diagnosis of lymphedema and who experienced any symptoms of lymphedema (in the last 3 months) on the 2004 survey.
Pairwise t-test with Bonferroni adjustment comparing women with diagnosed lymphedema to women without either lymphedema or arm symptoms, adjusted for age, baseline body mass index, and comorbidity index.
Pairwise t-test with Bonferroni adjustment comparing women with arm symptoms only to women without either lymphedema or arm symptoms, adjusted for age, baseline body mass index, and comorbidity index.