Table 2.

CML disease is readily transplantable to secondary recipients

Sorted cells	Number of transplanted cells	Transplanted animals	Incidence of CML (%)	Latency of disease (days±s.d.)
Sca1+Lin− (BM, Sca1-BCR-ABLp210 mice)	10.000	8	100	69±14
	1.000	8	100	85±11
Sca1+Lin− (BM, control mice)	10.000	8	0	NA
	1.000	8	0	NA
Sca1−Lin+ (BM, Sca1-BCR-ABLp210 mice)	1 × 105	8	0	NA
	1 × 106	8	0	NA
Sca1−Lin+ (BM, control mice)	1 × 105	8	0	NA
	1 × 106	8	0	NA
NA, not applicable.
Eight irradiated syngenic recipients mice per cohort were transplanted with the indicated number of cells. The diagnosis of CML was confirmed by histological and immunophenotypic examination of the ill recipient mice.