Table 3.

A comparison of the dose-volume metrics of 4D plans using the deliverable and 3D optimal methods: the mean and standard deviation (SD) of the dose-volume metric ratios averaged over all 12 patients; and p -values testing whether two distributions are statistically different. D_mean represents the dose received by mean volume of the PTV or OARs, D_A% the dose received by A% of volume of the PTV or OARs, and V_B the total volume of OARs receiving at least B Gy.

	PTV		Lungs-GTV		Spinal cord
	${\left(D_{\mathit{\text{mean}}}\right)}_{\mathit{\text{opt}}}^{\mathit{\text{del}}}$	${\left(D_{95\%}\right)}_{\mathit{\text{opt}}}^{\mathit{\text{del}}}$	${\left(D_{\mathit{\text{mean}}}\right)}_{\mathit{\text{opt}}}^{\mathit{\text{del}}}$	${\left(V_{20}\right)}_{\mathit{\text{opt}}}^{\mathit{\text{del}}}$	${\left(D_{0.1\%}\right)}_{\mathit{\text{opt}}}^{\mathit{\text{del}}}$
Mean ± SD	1.001 ± 0.002	0.995 ± 0.009	1.00 ± 0.02	1.01 ± 0.03	1.00 ± 0.02
min, max	0.999, 1.007	0.974, 1.009	0.97, 1.03	0.97, 1.08	0.96, 1.04
p	0.32	0.39	0.49	0.49	0.50
	Esophagus		Heart		Thorax-PTV
	${\left(D_{\mathit{\text{mean}}}\right)}_{\mathit{\text{opt}}}^{\mathit{\text{del}}}$	${\left(V_{55}\right)}_{\mathit{\text{opt}}}^{\mathit{\text{del}}}$	${\left(D_{\mathit{\text{mean}}}\right)}_{\mathit{\text{opt}}}^{\mathit{\text{del}}}$	${\left(V_{40}\right)}_{\mathit{\text{opt}}}^{\mathit{\text{del}}}$	${\left(D_{\mathit{\text{mean}}}\right)}_{\mathit{\text{opt}}}^{\mathit{\text{del}}}$
Mean ± SD	1.00 ± 0.02	1.02 ± 0.05	1.01 ± 0.03	1.00 ± 0.10	1.00 ± 0.01
min, max	0.96, 1.03	0.97, 1.11	0.95, 1.05	0.77, 1.20	0.97, 1.02
p	0.50	0.48	0.50	0.49	0.50