Table 3. Multivariate analysis (N=260).

	OS			DFS
	HR	95% CI	P-value	HR	95% CI	P-value
EGFR
<75th percentile	1	—	—	1	—	—
⩾75th percentile	1.71	1.00–2.93	0.050	1.52	0.95–2.44	0.079
HER2
<Median	1	—	—
⩾Median	1.84	1.07–3.17	0.027
HER3
<Median	1	—	—
⩾Median	0.53	0.30–0.91	0.021
HER4
<Median				1	—	—
⩾Median				0.58	0.36–0.93	0.022
Number of nodes
0–3	1	—	—	1	—	—
⩾4	2.42	1.08–5.34	0.032	2.70	1.38–5.28	0.004
Grade
I–II				1	—	—
III-Undifferentiated				1.52	0.96–2.41	0.071
Adjuvant hormonotherapy
No	1	—	—	1	—	—
Yes	0.48	0.23–0.99	0.50	0.52	0.27–0.99	0.046
Group of randomisation
E-T-CMF	1	—	—	1	—	—
E-CMF	0.85	0.51–1.41	0.526	0.93	0.60–1.45	0.928