Table 1. Characteristics of CRC patients.
|
MSA status
|
||||
|---|---|---|---|---|
| Total | MSI-H | MSS | P-valuea | |
| Number of patients | n=70 | n=37 (52.9) | n=33 (47.1) | |
| Age (years; median, range) | 50 (29–82)b | 51 (29–82) | 49 (29–73) | 0.92 |
| Gender | 0.16 | |||
| Male | 36 (51.4) | 16 (43.2) | 20 (60.6) | |
| Female | 34 (48.6) | 21 (56.8) | 13 (39.4) | |
| Localisation | <0.001 | |||
| Proximal | 31 (44.3) | 24 (64.9) | 7 (21.2) | |
| Distal | 28 (40.0) | 6 (16.2) | 22 (66.7) | |
| NA | 11 (15.7) | 7 (18.9) | 4 (12.1) | |
| Primary tumour | 0.37 | |||
| T1 | 4 (5.7) | 2 (5.4) | 2 (6.1) | |
| T2 | 13 (18.6) | 4 (10.8) | 9 (27.3) | |
| T3 | 41 (58.6) | 24 (64.9) | 17 (51.5) | |
| T4 | 8 (11.4) | 4 (10.8) | 4 (12.1) | |
| Tx | 4 (5.7) | 3 (8.1) | 1 (3.0) | |
| Lymph node status | 0.94 | |||
| N0 | 32 (45.7) | 17 (46.0) | 15 (45.5) | |
| N1/N2 | 27 (38.6) | 16 (43.2) | 11 (33.3) | |
| Nx | 11 (15.7) | 4 (10.8) | 7 (21.2) | |
| Distant metastasis | 0.49 | |||
| M0 | 42 (60) | 27 (73) | 15 (45.5) | |
| M1 | 8 (11.4) | 4 (10.8) | 4 (12.1) | |
| Mx | 20 (28.6) | 6 (16.2) | 14 (42.4) | |
| Stage of disease (UICC) | 0.64 | |||
| I | 10 (14.3) | 5 (13.5) | 5 (15.2) | |
| II | 17 (24.3) | 11 (29.7) | 6 (18.2) | |
| III | 14 (20.0) | 10 (27.0) | 4 (12.1) | |
| IV | 8 (11.4) | 4 (10.8) | 4 (12.1) | |
| NA | 21 (30.0) | 7 (18.9) | 14 (42.4) | |
NA=not analysable.
a
Fisher's exact test for categorical data and the Mann–Whitney test for age.
b
Numbers in parentheses indicate percentage values if not otherwise indicated.